High incidence of group A rotaviruses G4P[6] strains among children in Gyeonggi province of South Korea, from 2009 to 2012

  • Mun, Su-Kyoung; 
  • Cho, Han-Gil; 
  • Lee, Hyun-Kyung; 
  • Park, Sin-Hee; 
  • Park, Po-Hyun; 
  • ... Jeong, Hye-Sook; 
  • 외 2명
Citations

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초록

The genotype distribution of group A rotaviruses (RVAs) circulating in Gyeonggi province, South Korea between 2009 and 2012 was investigated. A total of 2619 stool specimens from sporadic acute gastroenteritis cases and 117 acute gastroenteritis outbreaks were analyzed. Among them, RVAs were detected from 263 (10.0%) sporadic cases and 3 (2.6%) outbreaks. The G4P[6] strains predominated (29.7%), followed by G1P[8] (19.4%), G2P[4] (15.6%), G3P[8] (13.3%) and G9P[8] (6.5%) strain. Especially 96.2% of the genotype G4P[6] strains were isolated from children < 1 year of age. Phylogenetic analysis revealed that genotype G4P[6] strains were members of sub-lineage Ie(G4) and Ia(P[6]). Intensified monitoring of RVAs, especially G4P[6] strains among young children, is essential to control RVA infections. (C) 2016 Elsevier B.V. All rights reserved.

키워드

Group A rotavirus; Acute gastroenteritis; Genotype; Children; GENETIC-CHARACTERIZATION; VACCINE; DIVERSITY; EMERGENCE; GENOTYPES; SEROTYPE; PROTEIN
제목
High incidence of group A rotaviruses G4P[6] strains among children in Gyeonggi province of South Korea, from 2009 to 2012
저자
Mun, Su-Kyoung; Cho, Han-Gil; Lee, Hyun-Kyung; Park, Sin-Hee; Park, Po-Hyun; Yoon, Mi-Hye; Jeong, Hye-Sook; Lim, Young-Hee
DOI
10.1016/j.meegid.2016.07.038
발행일
2016-10
유형
Article
저널명
Infection, Genetics and Evolution
권
44
페이지
351 ~ 355