Long-term PM2.5Exposure, Genome-wide DNA Methylation and Lung Function in Korean Adults

  • Han, Ye-Eun; 
  • Choi, Nak-Hyeon; 
  • Cho, Mi Jin; 
  • Kang, Min Gu; 
  • Kim, Young-Youl
Citations

SCOPUS

0

초록

This study aimed to investigate how the change of DNA methylation mediates the association between long-term exposure of PM2.5 and lung function (FVC, FEV1 and FEV1/FVC). Three CpGsites(cgl2233418 in CTDPI, cg00020794 in FAM38A and cg24202654 in GADI) were mediators of the association between PM2.5 and lung function. © 2021 IEEE.

키워드

DNA methylation; lung function; mediation analysis; PM2.5
제목
Long-term PM2.5Exposure, Genome-wide DNA Methylation and Lung Function in Korean Adults
저자
Han, Ye-Eun; Choi, Nak-Hyeon; Cho, Mi Jin; Kang, Min Gu; Kim, Young-Youl
DOI
10.1109/BIBM52615.2021.9669818
발행일
2021
유형
Conference paper
저널명
Proceedings - 2021 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2021
페이지
1652 ~ 1654