Generation of integration-free induced pluripotent stem cell line (KSCBi017-A) from peripheral blood mononuclear cells of a healthy male individual

  • Im, Young Sam; 
  • Yoo, Dae Hoon; 
  • Kim, Hyung-Eun; 
  • Kim, Yong-Ou; 
  • Oh, Ji Young
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초록

A human induced pluripotent stem cell (hiPSC) line, KSCBi017-A, was generated from a 50-year-old male individual using non-integrating episomal vectors expressing reprogramming factors. The generated hiPSCs were integration-free, expressed pluripotency markers, exhibited the potential for differentiation into three germ layers in vivo, and maintained the normal karyotype. This cell line can be used as a control for a disease model and is available from Korea National Stem Cell Bank.

키워드

VECTOR
제목
Generation of integration-free induced pluripotent stem cell line (KSCBi017-A) from peripheral blood mononuclear cells of a healthy male individual
저자
Im, Young Sam; Yoo, Dae Hoon; Kim, Hyung-Eun; Kim, Yong-Ou; Oh, Ji Young
DOI
10.1016/j.scr.2022.102965
발행일
2022-12
유형
Article
저널명
Stem Cell Research
권
65