The Use of Pluripotent Stem Cell for Personalized Cell Therapies against Neurological Disorders

  • Ha, Hye-Yeong; 
  • Jang, Si-Hyong; 
  • Jung, Ji-Won
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초록

Although there are a number of weaknesses for clinical use, pluripotent stem cells are valuable sources for patient-specific cell therapies against various diseases. Backed-up by a huge number of basic researches, neuronal differentiation mechanism is well established and pluripotent stem cell therapies against neurological disorders are getting closer to clinical application. However, there are increasing needs for standardization of the sourcing pluripotent stem cells by establishing stem cell registries and banking. Global harmonization will accelerate practical use of personalized therapies using pluripotent stem cells.

키워드

DIRECTED DIFFERENTIATION; NEURAL PROGENITORS; SELF-RENEWAL; PROMOTES DIFFERENTIATION; NIGRAL TRANSPLANTS; DOPAMINE NEURONS; HIGHLY EFFICIENT; IN-VITRO; POLYCOMB; INDUCTION
제목
The Use of Pluripotent Stem Cell for Personalized Cell Therapies against Neurological Disorders
저자
Ha, Hye-Yeong; Jang, Si-Hyong; Jung, Ji-Won
DOI
10.1155/2011/520816
발행일
2011
유형
Review
저널명
Journal of Biomedicine and Biotechnology